In 2020, Barbie with vitiligo was introduced to the Fashionistas line, followed by Ken with vitiligo in 2022; both dolls were designed in response to fan requests and consultations with dermatologists and other experts. In a statement, Mattel revealed that a prototype of the vitiligo Barbie, first showcased on the brand's official Instagram page, became its most 'liked' post ever and gained significant popularity, becoming one of the top five best sellers in the U.S. that year.

Vitiligo is a skin condition characterized by the loss of pigment in certain areas, leading to patches of lighter skin. It affects individuals of all ages, genders, and ethnicities, and can impact a person's self-esteem and body image.