In 1996, the 11th International AIDS Conference in Vancouver marked a turning point in the fight against HIV/AIDS. Researchers presented the Highly Active Antiretroviral Therapy (HAART), a medication regimen used to manage and treat human immunodeficiency virus type 1 (HIV-1). It is composed of several antiretroviral drugs. HAART reduces the risk of sexual transmission to partners to nearly zero in some studies, even among couples who engage in condomless sexual acts.